Mechanisms for evasion of the host immune response include the production of an antiphagocytic capsule, sequestering of host antibodies or antigen masking by Protein A, biofilm formation, intracellular survival, and blocking chemotaxis of leukocytes. ![]() The pathophysiology varies greatly depending on the type of S. Depending on the strains involved and the site of infection, these bacteria can cause invasive infections and/or toxin-mediated diseases. aureus are one the most common bacterial infections in humans and are the causative agents of multiple human infections, including bacteremia, infective endocarditis, skin and soft tissue infections (e.g., impetigo, folliculitis, furuncles, carbuncles, cellulitis, scalded skin syndrome, and others), osteomyelitis, septic arthritis, prosthetic device infections, pulmonary infections (e.g., pneumonia and empyema), gastroenteritis, meningitis, toxic shock syndrome, and urinary tract infections. ![]() MRSA strains tend to be resistant to methicillin, nafcillin, oxacillin, and cephalosporins. aureus strains that synthesize PBP-2A can grow in the presence of many antibiotics, and these MRSA strains are resistant to many antibiotics. PBP-2A has a lower affinity to bind to beta-lactams (and other penicillin-derived antibiotics) when compared to other PBPs, so PBP-2A continues to catalyze the synthesis of the bacterial cell wall even in the presence of many antibiotics. PBP-2a is a penicillin-binding protein (PBP), or essential bacterial cell wall enzyme that catalyzes the production of the peptidoglycan in the bacterial cell wall. The mec gene encodes the protein PBP-2a (penicillin-binding protein 2a). MRSA strains carry a mec gene on the bacterial chromosome, which is a component of the larger Staphylococcal chromosomal cassette mec (SCC mec) region, conferring resistance to multiple antibiotics depending on the SCC mec type. Typical biochemical identification tests include catalase positive (all pathogenic Staphylococcus species), coagulase positive (to distinguish Staphylococcus aureus from other Staphylococcus species), novobiocin sensitive (to distinguish from Staphylococcus saprophyticus), and mannitol fermentation positive (to distinguish from Staphylococcus epidermidis). These organisms can grow aerobically or anaerobically (facultative) and at temperatures between 18 C and 40 C. NOTE: This carrier does not include ballistic panels and provides no protection on its own.Staphylococcus aureus is Gram-positive bacteria (stain purple by Gram stain) that are cocci-shaped and tend to be arranged in clusters that are described as “grape-like.” On media, these organisms can grow in up to 10% salt, and colonies are often golden or yellow (aureus means golden or yellow). In the unfortunate event that you are shot while wearing your vest, we will replace it at no cost as long as a police report is provided during your 5 year warranty.ĥ Year manufacturer warranty on all ballistic panels and plates. Safe Life Defense stands behind our products and your personal protection. Exchanges must be within 30 days of delivery and in original condition. If you feel your vest does not fit properly, we will exchange your vest. Safe Life Defense guarantees the proper fit of your body armor. You may easily add rifle plates to your armor system within seconds, all without ever having to take off your vest. Prepared for extreme situations, the Safe Life Defense Tactical Carrier features top loading and expanded low profile rifle plate pockets in the front and rear for an extremely fast and comfortable fit. Our unique cut, Self Structured™ panels and thoughtful design, have proven to provide a level of comfort unmatched by any other vest on the market. Safe Life Defense armor is rated #1 in comfort among all soft body armor based on customer review. RATED #1 IN COMFORT AMONG ALL SOFT BODY ARMOR The drag handle system secures to itself with velcro for a sleek low profile fit. The rear name tag is optionally customizeable and removable. Highly durable, functional and stylish, the Safe Life Defense drag handle provides peace of mind and fast personal identification.
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